Polynucleotides

Polynucleotides are one of the most exciting innovations in skin rejuvenation. At Eden Medical, our doctor-led PDRN treatments work at a cellular level to repair, renew, and restore your skin from within, boosting collagen and elastin for firmer, smoother, healthier-looking skin.

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Treatment areas: Face and Eyes

What are Polynucleotides?

Polynucleotides, also known as PDRN, are a next-generation injectable treatment derived from purified DNA fragments. They work by stimulating the skin’s own repair mechanisms, encouraging collagen and elastin production, improving hydration, and accelerating cell renewal.

Unlike treatments that simply add volume or temporarily relax muscles, polynucleotides actively improve the health and quality of the skin itself. Results develop gradually and naturally over several weeks, making them an ideal treatment for those looking to address fine lines, skin laxity, dark circles, and overall skin texture without a surgical approach.

Treatments

All Polynucleotide Treatments

Explore our full range of PDRN skin regeneration treatments.

Polynucleotides Eyes

Targets fine lines, puffiness and dark circles in the delicate periorbital area.

Polynucleotides Rejuvenation (2%)

Full-face renewal improving texture, tone and deep hydration with a 2% concentration.

Polynucleotides Strong (2.5%)

Higher concentration formula for advanced lifting, laxity and deeper tissue repair.

Nationwide Coverage

Profhilo Treatment Available Across Ireland

Find Your Nearest Clinic

With clinics nationwide, there’s an Eden Medical close to you. Our doctor-led polynucleotide treatments are available in Dublin, Cork, Limerick, Galway, Belfast, Kilkenny, Waterford, Drogheda, Bray, Tralee, Killarney, Ennis, Carlow, Maynooth, Mullingar, Portlaoise, Ashbourne and more.

Improved Skin Texture

Polynucleotides promote the regeneration of skin cells at a cellular level, resulting in visibly smoother, more refined skin over time.

Enhanced Elasticity

By boosting collagen and elastin production, the treatment restores firmness and resilience to skin that has lost its youthful structure.

Reduced Fine Lines and Wrinkles

Stimulating natural cell turnover helps diminish the appearance of fine lines and wrinkles without the need for surgery or significant downtime.

Why Patients Choose Polynucleotides at Eden

Polynucleotides work differently to most injectable treatments. Rather than adding volume or freezing movement, they repair and regenerate the skin from within. This makes them an excellent choice for patients who want to improve overall skin health and quality, not just address individual lines or areas. Results develop gradually over two to four weeks and continue to improve with each session, making the treatment particularly effective as part of a longer-term skin health plan.

At Eden Medical, all polynucleotide treatments are administered by qualified medical practitioners who will assess your skin carefully and recommend the right formula and treatment plan for your needs.

Before and After Polynucleotides

Check out some of our incredible Polynucleotide results below.

Prices

From €250/ €275

Doctor/ Senior Doctor & Consultant

All Pricing

All pricing is available here.

Treatment Price List

Polynucleotide FAQs

What are polynucleotide injections?

Polynucleotide injections involve administering small amounts of polynucleotides into the skin to stimulate cell growth, collagen production, and skin regeneration.

Are polynucleotide injections safe?

Yes, polynucleotide injections are safe and well-tolerated by most individuals. They are derived from natural sources and are biocompatible with the human body.

Is the procedure painful?

Most patients experience minimal discomfort during the procedure. Any discomfort can be managed with topical anaesthetics if necessary.

How long does the procedure take?

The procedure typically takes up to 30 minutes, depending on the treatment area.

When will I see the results?

Results can appear within 2-14 days following the treatment.

Patient Experiences

What Our Patients Say

Cork

"Dr. Chrisna is amazing. To me, she is the best in Cork — her skills, knowledge, great sense of aesthetics but also very strong ethics are incredible. She even fixed issues I had post a treatment at another place. I don't know any better doctor in Cork. Highly recommended."

Cork

"Came today for my 2-week check-up on a gummy smile procedure. The ladies here are so kind and professional. I wasn't pushed to get anything extra. It is such a clean, tidy and organised practice and the waiting room is fab!"

Cork

"First timer and I do not know why I waited so long. Lovely clinic with amazing and friendly staff. Spotless and a great vibe! Thanks Dr. Ciara."

Cork

"A 5-star experience. The clinic was very welcoming and staff were very friendly. It was my first time having my lips done. They went through what to expect in great detail. At 50 I only wanted a very natural result — this was exactly what I came away with. Extremely happy."

Cork

"Beautiful spotless clean modern clinic. Friendly professional staff. Very informative consultation before my treatment with Dr Emma. Extremely happy with my treatment."

Cork

"I got veins removed from under my eyes using the Halo V laser. Lauren explained everything while she was doing it and it went so smoothly. The results were absolutely amazing after just one treatment. I'm absolutely thrilled with how fast it worked."

Dublin

"The most welcoming clinic and without a doubt the best in my experience. The honesty and genuine care was on another level. So happy with the results. You have a customer for life. Thank you."

Dublin

"I got the smallest 0.5ml filler and, oh my god, I'm addicted. My lips look so natural and amazing. Don't be scared the first day as they will be swollen, but once settled they look so amazing. The doctors are so skilled and professional — this clinic has me captive now!"

Dublin

"I had a really positive experience with Dr Meg. She was incredibly attentive, took the time to listen to what I wanted, and offered thoughtful, expert advice. I felt completely at ease and never rushed. I would definitely recommend her to anyone considering treatment."

Dublin

"Dr. Agatha took her time to understand the outcome I wanted. I took her advice and trusted her. I've never been happier with filler results — she kept the shape and evened out exactly what was needed. Thank you!"

Dublin

"Wonderful experience, really efficient and professional. Didn't feel a thing, the girl was so friendly and welcoming. Highly recommend."

Limerick

"Thank you very much for your help in correcting my face. I am so happy. The girls in Eden are very nice, they always explain everything clearly. I highly recommend Eden and all the girls who work there."

Limerick

"Great service. I had laser treatment with Laura, she was very professional and friendly, put me at ease straight away and explained the whole procedure thoroughly."

Limerick

"Wonderful experience with Dr. Clare, love visiting Eden — staff are always so friendly and very helpful. Mairead was so kind, informative and very friendly also."

Limerick

"I have had a few treatments at Eden Medical. The staff are absolutely lovely, very warm and welcoming from the moment you arrive. I would highly recommend Eden Medical Limerick."

Limerick

"I had a lovely experience with Dr. Claire this week. She was very professional and took great care with me. I hardly felt a thing. As always Mairead greeted me with such a lovely welcoming manner. Book immediately — you will not regret it. 10/10."

Galway

"Had such a positive experience at Eden Medical. The staff are very friendly and accommodating. I visited Dr. Miriam who answered all my questions, put me at ease and was very thorough. Delighted with my results and will definitely be visiting again!"

Galway

"Really lovely clinic and the staff were kind, helpful and thorough! I felt confident that I was in good hands and was at ease throughout the treatment."

Galway

"My first time getting lip filler and I was a bit nervous. Dr Méabh was so kind, patient and professional — I sailed through the procedure and was delighted with the results. Cannot recommend this place enough!"

Galway

"Always a lovely experience in Eden. I highly recommend Dr. Maebh and Dr. Miriam — both are fantastic doctors."

Galway

"I've had the Traptox treatment with Dr. Méabh twice to treat chronic trapezius/neck pain. She is a highly skilled professional who shows genuine interest in her patient's needs. The clinic is spacious, spotless and the receptionist is very kind and efficient."